But even with all of that, it's still better than Tkinter (at least on OS X 10.5). I don't know what it is, but I was having a hell of a time getting the clipboard to work properly in Tkinter once I tried to tweak my existing application, which is nothing more than two text labels, two text fields, and a button. My frustration got high enough that I just dove into wxPython and managed to completely re-implement the app in a night (which is faster than it took me to get the equivalent version to work in Tkinter).
But I am still not satisfied that I have found the best solution for someone like me who just wants a GUI toolkit to create really simple GUIs where I could have easily used a terminal-based approach instead. I am probably going to give a look at KWWidgets, PyGUI, PythonCard, and Twilight GUI. I would look at PyGTK, but until it runs natively on OS X I don't want to bother launching X11 for really simple applications.