Anyone at PyCon who saw my lightning talk or was around me throughout the conference will know what this PEP is about: getting rid of tuple parameters. Thanks to everyone at PyCon who provided arguments for their removal (basically Ka-Ping Yee was the only person who provided any argument for them to stay).
Collin Winter has already implemented a transform rule for 2to3 and Guido has already said he supports the idea. It looks like this PEP will get accepted for Py3K! Woohoo!